462351 Optimize and speed up the database

Hello, I have a site for upload and hosting files, [login to view URL] Site Database has become a big , 2.2 GB , And especially the "Files" table , 2.1 GB for this table "Files" only This caused for site the slow and sometimes stop, When you upload files and writing on this particular table "Files" you can see images for database on this link [login to view URL] Now, I need a specialist to resolve this problem, Optimize and speed up this database Solve the problem is a fundamental prerequisite, To pay The server and site works on, CENTOS OS , Perl/cgi , MySql , Apache webserver , Thanks and Best Regards.